NCT01529502View on ClinicalTrials.gov

Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting

PHASE2CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

March 31, 2012

Primary Completion Date

December 31, 2013

Study Completion Date

December 31, 2013

Conditions
Blood TransfusionEndothelial PhysiopathologyNitric OxidePulmonary Hypertension
Interventions
PROCEDURE

Red blood Cells auto-transfusion

Withdrawal from 14 overweight volunteers of one unit of red blood cells and auto-transfusion after 3 days storage time. The same 14 subjects will be included in every arm of the study.

PROCEDURE

Red blood Cells auto-transfusion

Withdrawal from the same 14 overweight volunteers of one unit of red blood cells and auto-transfusion after 40 days storage time.

DRUG

Inhaled Nitric Oxide (iNO) administration

Subjects will breath iNO (80ppm) for 10 minutes before, during and for one hour after the autologous old-blood transfusion.

Trial Locations (1)

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER

NCT01529502 - Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting | Biotech Hunter | Biotech Hunter