Iron & Alginate Study

NACompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

November 30, 2012

Study Completion Date

January 31, 2013

Conditions
Iron DeficiencyAnaemia
Interventions
DIETARY_SUPPLEMENT

alginate beads containing ferrous gluconate

After insertion of the cannula and collection of baseline blood sample a single dose of approximately 20mg of iron as ferrous gluconate incorporated into alginate beads (approximately 22.2g)and added to cola jelly (200ml) will be given to the volunteer together with 3 placebo capsules (each containing 50mg of dextrose)and cola drink (200ml). Once consumed, further blood samples will be taken at specified time points during 6 hour cannulation time. A minimum of 7 days wash out period will take place prior next intervention.

DIETARY_SUPPLEMENT

ferrous gluconate in a capsule

After insertion of the cannula and collection of baseline blood sample a single dose of approximately 20mg of iron as ferrous gluconate in a capsule and 2 placebo capsules (each containing 50mg of dextrose) followed by a cola jelly (200ml)and cola drink (200ml) will be given to the volunteer. Once consumed, further blood samples will be taken at specified time points during 6 hour cannulation time. A minimum of 7 days wash out period will take place prior next intervention.

DIETARY_SUPPLEMENT

ferrous gluconate in a capsule in presence of calcium

After insertion of the cannula and collection of baseline blood sample a single dose of approximately 20mg of iron as ferrous gluconate in a capsule together with 2 calcium capsules (each containing 300mg of calcium phosphate)followed by cola jelly (200ml) and cola drink(200ml)will be given to the volunteer . Once consumed, further blood samples will be taken at specified time points during 6 hour cannulation time. A minimum of 7 days wash out period will take place prior next intervention.

DIETARY_SUPPLEMENT

alginate beads with ferrous gluconate in presence of calcium

After insertion of the cannula and collection of baseline blood sample a single dose of approximately 20mg of iron as ferrous gluconate incorporated into alginate beads (approximately 22.2g)and added to cola jelly (200ml) will be given to the volunteer together with 2 calcium capsules (each containing 300mg of calcium as calcium phosphate, 1 placebo capsule (containing 50mg of dextrose)and cola drink (200ml). Once consumed, further blood samples will be taken at specified time points during 6 hour cannulation time. A minimum of 7 days wash out period will take place prior next intervention.

Trial Locations (1)

NR4 7TJ

Clinical Research and Trials Unit (CRTU)/ Norfolk and Norwich University Hospital (NNUH), Norwich

All Listed Sponsors
collaborator

Quadram Institute Bioscience

OTHER

lead

University of East Anglia

OTHER

NCT01528644 - Iron & Alginate Study | Biotech Hunter | Biotech Hunter