Study To Understand Efficacy And Safety Of Investigational Agent (PF-04937319) Compared To Approved Agent (Glimepiride) In Patients With Diabetes On Metformin

PHASE2CompletedINTERVENTIONAL
Enrollment

304

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

January 31, 2013

Study Completion Date

January 31, 2013

Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG

Placebo

Combination of tablets and capsules, a total of 3 pills/dose, administered once daily for 84-days

DRUG

PF-04937319 10 mg

Combination of tablets and capsules, dose of 10 mg, a total of 3 pills/dose, administered once daily for 84-days

DRUG

PF-04937319 50 mg

Combination of tablets and capsules, dose of 50 mg, a total of 3 pills/dose, administered once daily for 84-days

DRUG

PF-04937319 100 mg

Combination of tablets and capsules, dose of 100 mg, a total of 3 pills/dose, administered once daily for 84-days

DRUG

Glimepiride

Combination of tablets and capsules, dose of up to 6 mg, a total of 3 pills/dose, administered once daily for 84-days

Trial Locations (53)

100

National Taiwan University Hospital, Taipei

110

Taipei Medical University Hospital, Taipei

404

China Medical University Hospital, Taichung

1036

Synexus Magyarorszag Kft., Budapest

1083

Semmelweis Egyetem/I. sz. Belgyogyaszati Klinika, Budapest

1431

UMBAL Aleksandrovska, Klinika po endokrinologia i bolesti na obmyanata, Sofia

1606

VMA - MBAL - Sofia, Klinika po endokrinologia i bolesti na obmyanata, Sofia

2660

Dr. Kenessey Albert Korhaz-Rendelointezet/Belgyogyaszat, Balassagyarmat

5400

DKTs Akta Medika, Kabinet po endokrinologia, Sevlievo

6003

UMBAL Stara Zagora, Klinika po endokrinologia i bolesti na obmyanata, Stara Zagora

7002

MBAL - Ruse AD, Vtoro otdelenie po vatreshni bolesti, Rousse

7100

MBAL Yulia Vrevska - Byala, Otdelenie po vatreshni bolesti, Byala

8000

Fejer Megyei Szent Gyorgy Korhaz/II. Belgyogyaszati Osztaly, Székesfehérvár

23294

National Clinical Research - Richmond, Inc., Richmond

23502

National Clinical Research - Norfolk, Inc., Norfolk

28557

Diabetes & Endocrinology Consultants, PC, Morehead City

29464

Coastal Carolina Research Center, Mt. Pleasant

33027

South Broward Research, LLC, Pembroke Pines

34208

Meridien Research, Bradenton

37203

Clinical Research Associates, Inc., Nashville

37404

Chattanooga Medical Research, LLC, Chattanooga

Diagnostic Center, Chattanooga

37411

University Diabetes and Endocrine Consultants, Chattanooga

37620

Holston Medical Group, Bristol

45246

Sterling Research Group, Ltd., Cincinnati

45255

Community Research, Cincinnati

53209

Aurora Advanced Healthcare, Inc., Milwaukee

75230

Dallas Diabetes and Endocrine Center, Dallas

77802

DiscoveResearch, Inc., Bryan

78229

Clinical Trials of Texas, Inc., San Antonio

78728

Bristol Clinical Research, LLC, Austin

92103

California Research Foundation, San Diego

94598

Diablo Clinical Research, Inc., Walnut Creek

95661

Sierra Clinical Research, Roseville

96814

East-West Medical Research Institute, Honolulu

560060

BGS Global Hospital, Bangalore

02601

Clinical Research Center of Cape Cod, Inc., Hyannis

V3A 4H9

Glover Medical Clinic, Langley

V3S 2N6

Ocean West Research Clinic Inc., Surrey

R2V 4W3

Rivergrove Medical Clinic, Winnipeg

L6T 0G1

Aggarwal and Associates Limited, Brampton

N7G 1Y7

DCTM CLinical Trials Group Ltd., Strathroy

M9W 4L6

Manna Research, Toronto

G3K 2P8

Alpha Recherche Clinique, Québec

G6W 5M6

Pro-Recherche, Saint Romuald

J6V 1S8

Centre de cardiologie et de Recherche Clinique Pierre-Le Gardeur, Terrebonne

411 004

Deenanath Mangeshkar Hospital & Research Centre, Pune

411 011

Diabetes Unit, K.E.M. Hospital Research Centre, Pune

975 17

Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica, Banská Bystrica

045 01

Interna A Diabetologicka Ambulancia, Moldava nad Bodvou

940 01

FUNKYSTUFF, s.r.o., Nové Zámky

902 01

MEDIAB, s.r.o., Pezinok

010 01

MEDIVASA, s.r.o., Žilina

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT01517373 - Study To Understand Efficacy And Safety Of Investigational Agent (PF-04937319) Compared To Approved Agent (Glimepiride) In Patients With Diabetes On Metformin | Biotech Hunter | Biotech Hunter