Safety and Pharmacokinetic Study of Y242 in Adult Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

February 28, 2013

Study Completion Date

February 28, 2013

Conditions
Obesity
Interventions
DRUG

Y242

Single ascending dose: subcutaneous injection of 2, 7.5, 15, 30, 60 and 90 mg Y242 (Part A); Multiple ascending dose: Y242 single subcutaneous dose, administered once a week for 5 weeks (Part B)

DRUG

0.9% saline

Identical volume to that of Y242

Trial Locations (1)

HA1 3UJ

PAREXEL Early Phase Clinical Unit, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Medical Research Council

OTHER_GOV

lead

Imperial College London

OTHER