Multimodal Perioperative Pain Management

NACompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 31, 2001

Primary Completion Date

December 31, 2003

Study Completion Date

June 30, 2006

Conditions
Degenerative Spondylolisthesis
Interventions
DRUG

Postoperative epidural morphine

The control group received postoperative epidural morphine 0.4 mg/ml four times a day, epidural bupivacaine 2.5 mg/ml, 3-4 ml on request for 75 hours and a 7 day rehabilitation program.

DRUG

Local anaesthesia

Preemptively and posteruptively, the intervention group received local anaesthesia with bupivacaine 2.5 mg/ml, 10 + 10 ml posteriorly and 10 + 10 anteriorly; preemptive epidural analgesia with 3 ml lidocaine 20 mg/ml, 3 ml, 10 ml morphine 0.4 mg/ml plus 5 ml bupivacaine; postoperative continuous epidural analgesia for 72 hours with 250 ml with bupivacaine 1 mg/ml + morphine 50 ug/ml, and 0.5 ml epinephrine 1 mg/ml, 4 ml/hour, and after wound closure ketorolac 30 mg intravenously.

Trial Locations (1)

9000

Orthopaedic Research Unit, Aarhus University, Aalborg Hospital, Aalborg

All Listed Sponsors
collaborator

Vejle Hospital

OTHER

collaborator

Aarhus University Hospital

OTHER

collaborator

Copenhagen University Hospital, Denmark

OTHER

lead

Northern Orthopaedic Division, Denmark

OTHER

NCT01513564 - Multimodal Perioperative Pain Management | Biotech Hunter | Biotech Hunter