Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

147

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

April 30, 2027

Study Completion Date

April 30, 2027

Conditions
Esophageal Cancer
Interventions
RADIATION

Proton Beam Therapy (PBT)

1.8 Gy (Relative Biologic Equivalence ((RBE)) to be delivered to the periphery of the planning target volume (PTV) 1 time each day, 5 days a week (Monday through Friday) for up to 28 treatments.

RADIATION

Intensity Modulated Radiation Therapy (IMRT)

1.8 Gy to be delivered to the periphery of the planning target volume (PTV) 1 time each day, 5 days a week (Monday through Friday) for up to 28 treatments.

BEHAVIORAL

Questionnaires

Symptom and Quality of Life questionnaires completed at baseline, every week during radiation therapy, during break after radiation therapy, and during follow up phase.

Trial Locations (1)

77030

MD Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

Massachusetts General Hospital

OTHER

collaborator

National Cancer Institute (NCI)

NIH

lead

M.D. Anderson Cancer Center

OTHER