360
Participants
Start Date
November 16, 2011
Primary Completion Date
April 1, 2016
Study Completion Date
April 15, 2016
TDV
TDV 0.5 mL, injection, subcutaneously, once on Day 0 (first dose) and Day 90 (second dose). TDV comprised of 4 recombinant, live attenuated dengue virus strains: TDV-1, TDV-2, TDV-3 and TDV-4 containing 2\*10\^4 PFU, 5\*10\^4 PFU, 1\*10\^5 PFU, and 3\*10\^5 PFU respectively, total virus per dose: 4.7\*10\^5 PFU.
Placebo
TDV placebo-matching 0.5 mL injection, subcutaneously, once on Day 0 (first dose) and Day 90 (second dose).
Ponce School of Medicine, CAIMED Center, Ponce
Latin Clinical Trial Center, San Juan
Faculty of Tropical Medicine, Mahidol University, Bangkok
Phramongkutklao Hospital, Bangkok
National University Hospital, Singapore
Changi General Hospital, Singapore
Program For The Study and Control of Tropical Diseases, Medellín
University of Puerto Rico School of Medicine, San Juan
Lead Sponsor
Takeda
INDUSTRY