NCT01509300 - HLA-haploidentical Hematopoietic Stem Cell Transplantation for Children and Adolescents With Acute Leukemia, Myelodysplastic Syndrome and Solid Tumors | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 31, 2012

Primary Completion Date

December 31, 2013

Study Completion Date

March 31, 2014

Conditions

Acute LeukemiaMyelodysplastic SyndromeSolid Tumors

Interventions

BIOLOGICAL

anti-thymocyte globulin

On days -10 to -9

BIOLOGICAL

filgrastim

Beginning on day 4 and continuing until blood counts recover

RADIATION

Total body irradiation

2Gy D-6 to D-4

DRUG

Fludarabine

30mg/M2 once daily IV on days -8 to -4

DRUG

cyclophosphamide

60 mg/kg IV on day-3 and -2

DRUG

Tacrolimus

begin on 0

DRUG

Mycophenolate mofetil

begin on 0

DRUG

Rituximab

375mg/m2 on day +21

Trial Locations (1)

RECRUITING

Asan Medical Center, Seoul