BAX 326 Surgery Study in Hemophilia B Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

December 19, 2011

Primary Completion Date

May 15, 2014

Study Completion Date

May 15, 2014

Conditions
Hemophilia B
Interventions
BIOLOGICAL

Recombinant factor IX

Following a loading dose with BAX326, participants will receive BAX326 as a bolus infusion. The treatment regimen will be determined by the intensity and duration of the hemostatic challenge and the institution´s standard of care. The dose will be tailored to raise FIX concentration to at least 80%-100% of normal for major surgeries and to at least 30%-60% of normal for minor surgeries.

Trial Locations (14)

1233

"Specialized Haematological Hospital Joan Pavel", Sofia

2000

Instituto de Hematología y Medicina Clínica Rubén Dávoli, Rosario

79044

"State Institution Institute of Blood Pathology and Transfusion Medicine under the Academy of Medical Sciences of Ukraine", Lviv

125167

Hematology Research Center RAMS, Moscow

350007

Children's Territorial Clinical Hospital, Krasnodar

610027

Federal State Institution Kirov, Hematology and Blood Transfusion Research Institute under the Federal Agency for High-Tech Medical Care, Kirov

Unknown

Hospital Dr. Sotero del Rio, Santiago

Centro Medico Imbanaco, Santiago de Cali

Louis Turcanu Emergency Clinical Children´s Hospital, Timișoara

150 06

Klinika detska hematologie a onkologie, Fakultni Nemocnice Motol, Prague

93-510

Medical University Lodz, Copernicus Hospital, Department of Hematology, Lodz

00-579

Independent Public Pediatric Teaching Hospital, Clinical Department of Hematology and Pediatrics, Warsaw

02-776

Institute of Haematology and Transfusion Medicine, Warsaw

M13 9WL

Royal Manchester Children's Hospital, Department of Hematology, Manchester

All Listed Sponsors
lead

Baxalta now part of Shire

INDUSTRY

NCT01507896 - BAX 326 Surgery Study in Hemophilia B Patients | Biotech Hunter | Biotech Hunter