An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer (ACORN)

CompletedOBSERVATIONAL
Enrollment

719

Participants

Timeline

Start Date

July 6, 2012

Primary Completion Date

March 10, 2017

Study Completion Date

March 10, 2017

Conditions
Colorectal Cancer
Interventions
DRUG

Bevacizumab

Bevacizumab was administered as part of standard first-line treatment

DRUG

Capecitabine/Oxaliplatin

Capecitabine/oxaliplatin were administered along with bevacizumab as part of standard first-line treatment

DRUG

Fluorouracil/Folinic Acid/Oxaliplatin

Fluorouracil/folinic acid/oxaliplatin were administered along with bevacizumab as part of standard first-line treatment

DRUG

Capecitabine

Capecitabine was administered along with bevacizumab as part of standard first-line treatment

DRUG

Fluorouracil/Folinic Acid/Irinotecan

Fluorouracil/folinic acid/irinotecan were administered along with bevacizumab as part of standard first-line treatment

DRUG

Fluorouracil +/- Folinic Acid

Fluorouracil +/- folinic acid were administered along with bevacizumab as part of standard first-line treatment

Trial Locations (43)

BA1 3NG

Royal United Hospital Bath; Diabetes and Lipid Research, Wolfson Centre, Bath

SL2 4HL

Wexham Park Hospital; Oncology, Berkshire

B15 2TH

Queen Elizabeth Hospital, Birmingham

B9 5SS

Birmingham Heartlands Hospital; Dept of Oncology, Birmingham

DL14 6AD

Bishop Auckland Hospital;Oncology Department, Bishop Auckland

FY3 8NR

University Hospital of North Staffordhire, Blackpool

BD9 6RJ

Bradford Royal Infirmary; Dept of Medical Oncology C/O Ward15, Bradford

BS2 8ED

Bristol Haematology and Oncology Centre, Bristol

IP33 2QZ

West Suffolk Hospital Nhs Trust; Gi Corridor, Bury St Edmunds

CT1 3NG

Kent & Canterbury Hospital, Canterbury

CA2 7HY

Cumberland Infirmary; Oncology Department, Carlisle

CM1 7ET

Broomfield Hospital; Oncology, Chelsmford

TS19 8PE

University Hospital North Tees, Cleveland

HU16 5JQ

Castle Hill Hospital; Academic Oncology, Cottingham

DL3 6HX

Darlington Memorial Hospital, Darlington

DY1 2HQ

Russells Hall Hospital; Dept of Hematology, Dudley

DH15TW

University Hospital of North Durham; Oncology, Durham

HG2 8AY

Harrogate Hospital, Harrogate

HA1 3UJ

Northhwick Park Hospital;Oncology Department, Harrow

IP4 5PD

Ipswich Hospital; Oncology Pharmacy, Ipswich

DY11 6RJ

Kidderminster Hospital; Oncology Dept, Kidderminster

NW3 2QG

Royal Free Hospital; Dept of Oncology, London

SE1 9RT

Guys Hosp./Med. Onc./3rd Fl. T; Clinical Trial Office, London

SE18 4QH

Queen Elizabeth Hospital, London

SK10 3BL

Macclesfield District General Hospital, Macclesfield

ME16 9QQ

Maidstone & Tonbridge Wells Hospital; Kent Oncology Center, Maidstone

TS4 3BW

The James Cook University Hospital, Middlesbrough

NE7 7DN

Freeman Hospital, Newcastle upon Tyne

NE29 8NH

North Tyneside General Hospital, North Shields

HA6 2RN

Mount Vernon Cancer Centre, Northwood

NG5 1PB

Nottingham University Hospitals City Campus, Nottingham

PE3 9GZ

Peterborough City Hospital, Edith Cavell Campus; Oncology Department, Peterborough

PL6 8DH

Derriford Hospital; Gastroenterology, Plymouth

RM7 0AG

Queen's Hospital, Romford

DN16 7BH

Scunthorpe General Hospital; Dept of Oncology, Scunthorpe

ST16 3SA

Stafford Hospital; Oncology Department, Stafford

SM2 5PT

The Royal Marsden Hospital, Sutton

SN3 6BB

Great Western Hospital, Swindon Cancer Research Unit; Osprey Unit Level 3, Swindon

TQ2 7AA

Torbay Hospital; Oncology, Torquay

TR1 3LJ

Royal Cornwall Hospital; Dept of Clinical Oncology, Truro

WS2 9PS

Walsall Manor Hospital, Walsall

SO22 5DG

Royal Hampshire County Hospital; Winchester & Andover Breast Unit, Winchester

WV10 0QP

The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT01506167 - An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer (ACORN) | Biotech Hunter | Biotech Hunter