14
Participants
Start Date
December 31, 2011
Primary Completion Date
December 31, 2014
Study Completion Date
December 31, 2014
TPI 287
Subjects will receive six cycles of intravenous (IV) TPI 287 at a dose of 125 mg/m2 on Days 1, 8 and 15 of a 28-day cycle.
Temozolomide
Oral (PO) Temozolomide at a dose of 100mg/m2 on days 1-5 of each 28 day cycle
Irinotecan
Intravenous (IV) Irinotecan at a dose of 10mg/m2 on days 1-5 and 8-12 of each 28 day cycle.
Levine Children's Hospital, Charlotte
Arnold Palmer Hospital for Children- MD Anderson, Orlando
Helen DeVos Children's Hospital, Grand Rapids
Cardinal Glennon Children's Medical Center, St Louis
Children's Mercy Hospitals and Clinics, Kansas City
Rady Children's Hospital, San Diego
Phoenix Children's Hospital, Phoenix
Connecticut Children's Hospital, Hartford
Collaborators (1)
Cortice Biosciences, Inc.
INDUSTRY
Giselle Sholler
OTHER