Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis

PHASE3CompletedINTERVENTIONAL
Enrollment

193

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

February 28, 2013

Study Completion Date

March 31, 2013

Conditions
Anterior Uveitis
Interventions
DRUG

40 mg/mL Dexamethasone phosphate ophthalmic solution

Transscleral iontophoresis delivery of EGP-437 (dexamethasone phosphate formulated for ocular iontophoresis)

DRUG

Prednisolone Acetate (1%) Eyedrops

Prednisolone acetate (1%) eyedrops

DRUG

100 mM sodium citrate buffer solution

Transscleral iontophoresis delivery of 100 mM Sodium citrate buffer solution

DRUG

Placebo Eyedrops

Placebo Eyedrops

Trial Locations (39)

10003

The New York Eye and Ear Infirmary, New York

19104

Scheie Eye Institute, Philadelphia

19107

Mid-Atlantic Retina, Philadelphia

21287

Wilmer Eye Institute, Baltimore

23502

Virginia Eye Consultants, Norfolk

28105

Charlotte Eye Ear Nose and Throat Associates, Matthews

30322

Emory Eye Center, Atlanta

30742

Advanced Eye Care, Fort Oglethorpe

32204

Levenson Eye Associates, Jacksonville

33136

Bascom Palmer Eye Institute, Miami

33321

Logan Ophthalmic Research, Tamarac

34209

The Eye Associates of Manatee, LLP, Bradenton

35233

Department of Ophthalmology at University of Alabama at Birmingham, Birmingham

38104

Southern College of Optometry, Memphis

46290

Raj K. Maturi, M.D. PC, Indianapolis

60612

Illinois Retina Associates, Chicago

63017

Lifelong Vision Foundation, Chesterfield

63090

Comprehensive Eye Care Ltd., Washington

64111

Tauber Eye Center, Kansas City

77025

Houston Eye Associates, Houston

78240

Medical Center Ophthalmology Associates, San Antonio

78705

Austin Retina Associates, Austin

80120

Corneal Consultants of Colorado, Littleton

80401

Colorado Retina Associates, Golden

85020

Associated Retina Consultants, Phoenix

85225

Arizona Eye Center, Chandler

90033

Doheny Eye Medical Group, Los Angeles

90211

Retina-Vitreous Associates Medical Group, Beverly Hills

92705

Orange County Retina Medical Group, Santa Ana

97239

Casey Eye Institute, Portland

99204

Spokane Eye Clinical Research, Spokane

06606

Connecticut Retina Consultants, LLC, Bridgeport

06518

Eye Center of Southern Connecticut, Hamden

06510

Yale Eye Center, New Haven

04605

Ellsworth Uveitis and Retina Care, Ellsworth

02114

Massachusetts Eye and Ear Infirmary, Boston

Ophthalmic Consultants of Boston, Boston

02142

Massachusetts Eye Research and Surgery Institution, Cambridge

07650

Metropolitan Eye Research and Surgery Institute, Palisades Park

Sponsors
All Listed Sponsors
lead

Eyegate Pharmaceuticals, Inc.

INDUSTRY