Capecitabine in the Perioperative Treatment of Rectal Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

401

Participants

Timeline

Start Date

March 31, 2002

Primary Completion Date

March 31, 2011

Study Completion Date

March 31, 2011

Conditions
Rectal Cancer
Interventions
DRUG

Capecitabine

Capecitabine standard therapy (i.e. 2,500 mg/sqm) x 5 cycles plus 1 cycle of capecitabine based chemoradiotherapy (1.650 mg/sqm)

DRUG

5-FU

4 cycles of bolus 5-FU (500 mg/sqm) and 1 cycle of 5-FU based chemoradiotherapy (either 1,000 mg/sqm/day infusional 5-Fu days 1-5 and 29-33 or 225 mg/sqm/day infusional 5-Fu throughout the time of chemoradiotherapy)

Trial Locations (14)

Unknown

Dr Martina Grunewald, Aschersleben

Dr Hans Walter Lindemann, Hagen

Prof Hartmut Link, Kaiserslautern

Dr Elisabeth Fritz, Koblenz

Dr Stephan Kremers, Lebach

Dr Lothar Müller, Leer

Dr Christain Constantin, Lemgo

Dr Erika Kettner, Magdeburg

Dr Markus Moehler, Mainz

Dr Udo Hieber, Mannheim

Prof Ralf Hofheinz, Mannheim

Dr Matthias Hipp, Regensburg

Prof Axel Matzdorff, Saarbrücken

Dr Stephan Laechelt, Tübingen

All Listed Sponsors
lead

Universitätsmedizin Mannheim

OTHER

NCT01500993 - Capecitabine in the Perioperative Treatment of Rectal Cancer | Biotech Hunter | Biotech Hunter