NCT01500980View on ClinicalTrials.gov

Malaria Challenge in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

July 31, 2012

Study Completion Date

November 30, 2012

Conditions
Malaria
Interventions
BIOLOGICAL

P. falciparum infection

P. falciparum (NF54 strain) infection delivered by the bites of 12 - 15 infected A. stephensi mosquitos

DRUG

Chloroquine

Weekly chloroquine dosing (600 mg loading dose, 300 mg thereafter)

DRUG

Primaquine

Primaquine (45 mg) on day 2 or 3 post ITV infection

DRUG

Primaquine

Primaquine (45 mg) on day 2 or 3 (pending results of pilot study) post ITV infection

Trial Locations (1)

98109

Seattle Biomedical Research Institute's Malaria Clinical Trials Center, Seattle

All Listed Sponsors
lead

Seattle Children's Hospital

OTHER

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