The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of Long De Novo Coronary Artery Lesions (PLATINUM LL)

PHASE3CompletedINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

March 31, 2011

Study Completion Date

May 31, 2015

Conditions
Coronary Artery Disease
Interventions
DEVICE

PROMUS Element Coronary Stent System

PROMUS Element is a device/drug combination product composed of two components, a device (coronary stent system including a platinum chromium stent platform) and a drug product (a formulation of everolimus contained in a polymer coating).

DRUG

Aspirin

Patients are required to take aspirin indefinitely after stent implant. It is recommended that aspirin 162-325 mg daily be given for at least 6 months after stent placement and that aspirin 75-162 mg daily be given indefinitely thereafter.

DRUG

Thienopyridine

Patients must be treated with one of the following thienopyridines for at least 6 months following the index procedure: clopidogrel 75 mg daily; or ticlopidine 250 mg twice daily; or prasugrel (outside the United States and if approved at the time of the procedure). If used, the prescribed dose should be in accordance with approved country-specific labeling. In patients not at high risk of bleeding, thienopyridine treatment should continue for at least 12 months after stent implant.

Trial Locations (30)

3065

St. Vincents Public,, Fitzroy

3168

Monash Medical Centre, Clayton

3600

Ziekenhuis Oost Limburg, Genk

10032

Columbia University Medical Center, New York

27401

Moses H. Cone Memorial Hospital/LeBauer Cardiovascular Research Foundation, Greensboro

27610

Wake Medical Center, Raleigh

31076

Clinique Pasteur, Toulouse

32803

Florida Hospital, Orlando

34471

MediQuest Research Group Inc. at Munroe Regional Medical Center, Ocala

38301

Jackson-Madison County General Hospital, Jackson

38801

North Mississippi Medical Center, Tupelo

43210

Ohio State University Medical Center, Columbus

43214

Ohio Health Research and Innovation Institute, Columbus

43608

Mercy St. Vincent Medical Center, Toledo

48073

William Beaumont Hospital, Royal Oak

49770

Northern Michigan Hospital, Petoskey

55407

Abbott Northwestern Hospital, Minneapolis

73120

Oklahoma Foundation for Cardiovascular Research, Oklahoma City

78229

TexSAn Heart Hospital, San Antonio

92037

Scripps Clinic, La Jolla

92120

Alvarado Hospital, San Diego

95819

Mercy General Hospital, Sacramento

97225

Providence St. Vincent Medical Center, Portland

99204

Providence Health & Services - Washington, Spokane

04102

Maine Medical Center, Portland

B-3000

UZ Gasthuisberg, Leuven

Unknown

Shonan Kamakura General Hospital, Kamakura-shi

Sakurabashi Watanabe Hospital, Osaka

LV-1002

P. Stradins University Hospital, Riga

0622

North Shore Hospital, Takapuna

Sponsors
All Listed Sponsors
lead

Boston Scientific Corporation

INDUSTRY