Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans

PHASE4CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

May 31, 2011

Primary Completion Date

October 31, 2011

Study Completion Date

December 31, 2011

Conditions
Effects of 2 Mu-opiates on Gastrointestinal Transit
Interventions
DRUG

Tapentadol

Subjects received tapentadol immediate release formulation, 75 mg three times per day (tid) for 48 hours.

DRUG

Oxycodone

Subjects received oxycodone immediate release formulation, 5 mg three times per day (tid) for 48 hours.

DRUG

Placebo

Subjects received placebo three times per day (tid) for 48 hours.

Trial Locations (1)

55905

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Center for Research Resources (NCRR)

NIH

lead

Mayo Clinic

OTHER