Nocturnal Transnasal Insufflation (nTNI)

NACompletedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

August 31, 2011

Primary Completion Date

July 31, 2012

Study Completion Date

July 31, 2012

Conditions
COPDHypercapnia
Interventions
DEVICE

humidified transnasal insufflation (TNI20oxy)

The alternative breathing support with TNI supplies COPD patients with 20L/min of warm humidified air. This method may be applicable to wash out the dead space between glottis and nasal opening. Pre-investigations have shown that 45 minutes of TNI during daytime reduced PCO2 and respiratory rate compared to application of oxygen alone.Transcutaneous PCO2 is measured over night. A capillary blood gas analysis (BGA) is carried out at beginning and end of each measurement night.

OTHER

overnight oxygen treatment with individual flow rate

The patient is treated with his individual oxygene flow rate. Transcutaneous PCO2 is measured over night. A capillary blood gas analysis (BGA) is carried out at beginning and end of each measurement night.

Trial Locations (1)

58091

Helios Klinik Hagen Ambrock, Hagen

All Listed Sponsors
collaborator

TNI Medical AG

INDUSTRY

lead

Institut für Pneumologie Hagen Ambrock eV

INDUSTRY

NCT01499550 - Nocturnal Transnasal Insufflation (nTNI) | Biotech Hunter | Biotech Hunter