140
Participants
Start Date
November 30, 2011
Primary Completion Date
February 28, 2015
Study Completion Date
February 28, 2015
Acetazolamide
"Daily morning ABGA:~* If actual bicarbonate \> 26 mmol/L and pH \> 7.35: administration of enteral capsule of acetazolamide 500 mg .~* If actual bicarbonate \> 26 mmol/L and pH \<= 7.35, increase minute ventilation to reach pH \> 7.35 and then administer enteral capsule of acetazolamide 500 mg.~* If actual bicarbonate \<= 26 mmol/L: omit treatment that day."
Placebo
"Daily morning ABGA:~* If actual bicarbonate \> 26 mmol/L and pH \> 7.35: administration of enteral capsule of placebo.~* If actual bicarbonate \> 26 mmol/L and pH \<= 7.35, increase minute ventilation to reach pH \> 7.35 and then administer enteral capsule of placebo.~* If actual bicarbonate \<= 26 mmol/L: omit treatment that day."
Hospital Universitario Infanta Leonor, Madrid
Fundación Jiménez Díaz, Madrid
Hospital de Manacor, Manacor
Hospital Son Espases, Palma de Mallorca
Hospital Son Llàtzer, Palma de Mallorca
Hospital de la Santa Creu i Sant Pau, Barcelona
Fundació Hospital Asil de Granollers, Granollers
Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despí
Hospital Son Llatzer
OTHER