90
Participants
Start Date
March 31, 2011
Primary Completion Date
June 30, 2011
Study Completion Date
October 31, 2011
Lidocaine/tetracaine patch
The lidocaine/tetracaine patch topical anesthetic patch contains 70 mg each of lidocaine and tetracaine. The central area of each patch consists of a Controlled Heat Assisted Drug Delivery pod which is designed to warm the skin to 26-34°C, theoretically enhancing drug absorption and allowing application just 20 minutes before percutaneous procedures. A active or placebo patch was placed on each patient's wrist in the region of the maximum radial artery pulsation. After 20 minutes, the patch was removed.
Placebo Patch
A placebo patch was placed on each patient's wrist in the region of the maximum radial artery pulsation. After 20 minutes, the patch was removed.
Subcutaneous injection of 0.5 ml Lidocain 1%
After removing the patch, a blinded investigator injected 0.5 ml of 1% lidocaine solution. Three minutes after injection, an attempt was made to cannulate the radial artery with a 20-gauge catheter.
Subcutaneous injection of saline
After removing the patch, a blinded investigator injected 0.5 ml saline solution. Three minutes after injection, an attempt was made to cannulate the radial artery with a 20-gauge catheter.
Cleveland Clinic Department of Outcomes Research, Cleveland
Medical University of Vienna, Vienna
Population Health Research Institute, McMaster University, Hamilton
Collaborators (1)
The Cleveland Clinic
OTHER
Population Health Research Institute
OTHER
Medical University of Vienna
OTHER