Study to Evaluate the Safety, Tolerability and the Effect of BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects With Mild Alzheimer's Disease

PHASE1CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

October 31, 2013

Study Completion Date

October 31, 2013

Conditions
Alzheimer's Disease
Interventions
DRUG

BMS-241027

Intravenous (IV), 0.003 mg/kg, Once Weekly, 9 weeks

DRUG

BMS-241027

Intravenous (IV), 0.01 mg/kg, Once Weekly, 9 weeks

DRUG

BMS-241027

Intravenous (IV), 0.03 mg/kg, Once Weekly, 9 weeks

DRUG

Placebo matching BMS-241027

Intravenous (IV), 0.0 mg/kg, Once Weekly, 9 weeks

Trial Locations (24)

14050

Local Institution, Berlin

19046

The Clinical Trial Center, Llc, Jenkintown

19104

Hospital Of The University Of Pennsylvania, Philadelphia

Penn Memory Center, Philadelphia

31059

Local Institution, Toulouse

32806

Compass Research, Llc, Orlando

33410

Palm Beach Neurological Center Advanced Research Consultants, Palm Beach Gardens

43210

The Ohio State University, Columbus

48824

Michigan State University, East Lansing

59037

Local Institution, Lille

60007

Alexian Brothers Neurosciences Institute Clinical Research, Elk Grove Village

69115

Local Institution, Heidelberg

75013

Local Institution, Paris

80304

Alpine Clinical Research Center, Inc., Boulder

84106

Lifetree Clinical Research, Salt Lake City

90806

Long Beach

92801

Anaheim Clinical Trials Llc, Anaheim

94158

Ucsf Memory And Aging Center, San Francisco

06824

Associated Neurologists Of Southern Connecticut, P.C., Fairfield

02115

Brigham And Women'S Hospital, Boston

N6C 5J1

Local Institution, London

M3B 2S7

Local Institution, Toronto

J4V 2J2

Local Institution, Greenfield Park

141 86

Local Institution, Stockholm

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY