305
Participants
Start Date
March 31, 2012
Primary Completion Date
January 31, 2015
Study Completion Date
February 5, 2018
Prompt Panretinal Photocoagulation
Panretinal photocoagulation alone at baseline (full session completed within 56 days).
0.5-mg Ranibizumab
Intravitreal injection of 0.5 mg ranibizumab (Lucentis™) at baseline and up to every 4 weeks using defined retreatment criteria.
Deferred panretinal photocoagulation
PRP is deferred until failure/futility criteria for intravitreal injection are met.
The New York Eye and Ear Infirmary/Faculty Eye Practice, New York
Retina-Vitreous Surgeons of Central New York, PC, Syracuse
University of Rochester, Rochester
Retina Vitrous Consultants, Pittsburgh
Penn State College of Medicine, Hershey
Elman Retina Group, P.A., Baltimore
Charlotte Eye, Ear, Nose and Throat Assoc., PA, Charlotte
Carolina Retina Center, Columbia
Southeast Retina Center, P.C., Augusta
Fort Lauderdale Eye Institute, Plantation
Central Florida Retina Institute, Lakeland
Retina Consultants of Southwest Florida, Fort Myers
Retina Associates of Sarasota, Venice
Ocala Eye Retina Consultants, Ocala
Southeastern Retina Associates, PC, Kingsport
Southeastern Retina Associates, P.C., Knoxville
Eye Surgical Associates, Lincoln
Paducah Retinal Center, Paducah
Retina Associates of Cleveland, Inc., Beachwood
Raj K. Maturi, M.D., P.C., Indianapolis
John-Kenyon American Eye Institute, New Albany
Retina Vitrous Center, Grand Blanc
Wolfe Eye Clinic, West Des Moines
Medical College of Wiconsin, Milwaukee
North Shore University Health System, Glenview
Barnes Retina Institute, St Louis
Texas Retina Associates, Dallas
Retina and Vitreous of Texas, Houston
Baylor Eye Physicians and Surgeons, Houston
Retinal Consultants of San Antonio, San Antonio
Valley Retina Institute, McAllen
Austin Retina Associates, Austin
Retina Research Center, Austin
Texas Retina Associates, Lubbock
Retinal Consultants of AZ, Phoenix
Southern California Desert Retina Consultants, MC, Palm Springs
Loma Linda University Health Care, Dept. of Ophthalmology, Loma Linda
California Retina Consultants, Santa Barbara
Bay Area Retina Associates, Walnut Creek
Retina Northwest, PC, Portland
Casey Eye Institute, Portland
University of Washington Medical Center, Seattle
Spokane Eye Clinic, Spokane
New England Retina Associates, Trumbull
Retina and Vitreous Associates of Kentucky, Lexington
Vitreo-Retinal Associates, PC, Worcester
University of North Carolina, Chapel Hill
Family Eye Group, Lancaster
Lead Sponsor
Collaborators (1)
National Eye Institute (NEI)
NIH
Genentech, Inc.
INDUSTRY
Jaeb Center for Health Research
OTHER