Tenofovir in Late Pregnancy to Prevent Vertical Transmission of Hepatitis B Virus

PHASE4CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

March 1, 2012

Primary Completion Date

April 28, 2014

Study Completion Date

June 28, 2018

Conditions
Hepatitis B InfectionChronic InfectionViremia
Interventions
DRUG

TDF treatment

About 100 mothers treated with tenofovir from 30-32 weeks of pregnancy to the week 4 of postpartum, then observed to the end of the study at post-partum week 28, paired infants received standard HBV prophylaxis.

Trial Locations (5)

130062

Hepatobiliary Disease Hospital of Jilin Province, Changchun

210003

The Second Affiliated Hospital of the Southeast University, Nanjing

400038

Southwest Hospital, Chongqing

473000

Nanyang Central Hospital, Nanyang

050021

The Fifth Hospital of Shijiazhuang, Shijiazhuang

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Gilead Sciences

INDUSTRY

lead

New Discovery LLC

INDUSTRY