Dose Escalation Study of Pazopanib Plus TH-302

PHASE1CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

February 28, 2013

Study Completion Date

March 31, 2014

Conditions
Solid Tumors
Interventions
DRUG

Pazopanib and TH-302

Pazopanib 800 mg daily TH-302 IV on Days 1, 8, 15 at MTD Subjects will receive this regimen until disease progression.

Trial Locations (1)

27710

Duke Cancer Institute, Durham

All Listed Sponsors
collaborator

National Comprehensive Cancer Network

NETWORK

collaborator

GlaxoSmithKline

INDUSTRY

collaborator

Threshold Pharmaceuticals

INDUSTRY

lead

Herbert Hurwitz, MD

OTHER

NCT01485042 - Dose Escalation Study of Pazopanib Plus TH-302 | Biotech Hunter | Biotech Hunter