262
Participants
Start Date
April 30, 2012
Primary Completion Date
April 30, 2015
Study Completion Date
April 30, 2015
Pegylated-Interferon Alfa 2b (PEG-IFN)
1.5 mcg/kg subcutaneously (SC) once a week (based on participant's weight at entry) for up to 48 weeks depending on cirrhosis status and, in Group A, Week 8 HCV viral response.
Ribavirin (RBV)
800-1400 mg orally per day with food (based on participant's weight at entry) for up to 48 weeks depending on cirrhosis status and, in Group A, Week 8 HCV viral response.
Boceprevir (BOC)
800 mg orally every 8 hours with food from Week 5 to up to Week 48 depending on cirrhosis status and, in Group A, Week 8 HCV viral response
Weill Cornell Chelsea CRS, New York
Weill Cornell Uptown CRS, New York
Bronx-Lebanon Hosp. Ctr. CRS, The Bronx
University of Rochester Adult HIV Therapeutic Strategies Network CRS, Rochester
University of Pittsburgh CRS, Pittsburgh
Penn Therapeutics, CRS, Philadelphia
Georgetown University CRS (GU CRS), Washington D.C.
IHV Baltimore Treatment CRS, Baltimore
Johns Hopkins University CRS, Baltimore
Virginia Commonwealth University CRS, Richmond
Chapel Hill CRS, Chapel Hill
Duke Univ. Med. Ctr. Adult CRS, Durham
Alabama CRS, Birmingham
Vanderbilt Therapeutics (VT) CRS, Nashville
Ohio State University CRS, Columbus
Case Clinical Research Site, Cleveland
MetroHealth CRS, Cleveland
Cincinnati Clinical Research Site, Cincinnati
Wayne State Univ. CRS, Detroit
Henry Ford Hosp. CRS, Detroit
Northwestern University CRS, Chicago
Rush University CRS, Chicago
Trinity Health and Wellness Center CRS, Dallas
Houston AIDS Research Team CRS, Houston
University of Colorado Hospital CRS, Aurora
Denver Public Health CRS, Denver
UCLA CARE Center CRS, Los Angeles
Harbor-UCLA CRS, Torrance
UCSD Antiviral Research Center CRS, San Diego
Ucsf Hiv/Aids Crs, San Francisco
University of Southern California CRS, Los Angeles
Stanford AIDS Clinical Trials Unit CRS, Palo Alto
The Ponce de Leon Center CRS, Atlanta
Massachusetts General Hospital CRS (MGH CRS), Boston
Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS, Boston
Bmc Actg Crs, Boston
Washington University Therapeutics (WT) CRS, St Louis
Cooper Univ. Hosp. CRS, Camden
New Jersey Medical School Clinical Research Center CRS, Newark
Columbia P&S CRS, New York
The Miriam Hospital Clinical Research Site (TMH CRS) CRS, Providence
University of Washington AIDS CRS, Seattle
Puerto Rico AIDS Clinical Trials Unit CRS, San Juan
National Institute of Allergy and Infectious Diseases (NIAID)
NIH