Safety and Efficacy of Treprostinil in Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplantation

PHASE1CompletedINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

December 31, 2012

Primary Completion Date

May 18, 2019

Study Completion Date

November 24, 2019

Conditions
Ischemia Reperfusion Injury
Interventions
DRUG

Treprostinil

"The Treatment Phase will begin at the initiation of Treprostinil after induction of anesthesia for the transplant surgery and continues throughout the surgery and for approximately a total of 120 hours.~Treatment phase activities include:~• Initiation of Treprostinil after the patient is hemodynamically stable following transplant surgery. (Treprostinil dosing will follow a standard 3 + 3 phase 1 design."

Trial Locations (2)

15261

Abhinav Humar, Pittsburgh

University of Pittsburgh Medical Center, Pittsburgh

All Listed Sponsors
lead

Abhinav Humar, MD

OTHER

NCT01481974 - Safety and Efficacy of Treprostinil in Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplantation | Biotech Hunter | Biotech Hunter