A Study to Establish the Efficacy of QBX258 in Patients With Moderate to Severe Asthma

PHASE2CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

February 28, 2015

Study Completion Date

February 28, 2015

Conditions
Asthma
Interventions
DRUG

QBX258

QBX258 infusion, a combination of VAK694 and QAX576, was supplied to the Investigator as open label bulk medication. The planned dose of VAK694 (lyophilisate in vial, 150 mg/vial), was 3 mg/kg. The planned dose of QAX576 (lyophilisate in vial, 150 mg/vial), was 6 mg/kg.

DRUG

Placebo

The placebo infusion was an equal volume of 5% dextrose for infusion and was provided by the clinical site.

Trial Locations (20)

10117

Novartis Investigative Site, Berlin

27157

Novartis Investigative Site, Winston-Salem

27607

Novartis Investigative Site, Raleigh

29303

Novartis Investigative Site, Spartanburg

33180

Novartis Investigative Site, Aventura

55402

Novartis Investigative Site, Minneapolis

60596

Novartis Investigative Site, Frankfurt

63110

Novartis Investigative Site, St Louis

65187

Novartis Investigative Site, Wiesbaden

73120

Novartis Investigative Site, Oklahoma City

80206

Novartis Investigative Site, Denver

80230

Novartis Investigative Site, Denver

90274

Novartis Investigative Site, Rolling Hills Estates

91108

Novartis Investigative Site, San Marino

92506

Novartis Investigative Site, Riverside

92801

Novartis Investigative Site, Anaheim

02115

Novartis Investigative Site, Boston

97504-8741

Novartis Investigative Site, Medford

SE11YR

Novartis Investigative Site, London

M23 9QZ

Novartis Investigative Site, Manchester

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY