Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathy

PHASE2CompletedINTERVENTIONAL
Enrollment

104

Participants

Timeline

Start Date

August 31, 2012

Primary Completion Date

March 12, 2014

Study Completion Date

June 30, 2014

Conditions
Painful Diabetic Neuropathies
Interventions
BIOLOGICAL

Low Dose: 16 mg Engensis (VM202)

"Subjects in the Low Dose Group (8mg VM202 / leg) will receive the following intramuscular injections in each calf:~Day 0 - 32 injections / calf:~• 16 injections of 0.5mL of VM202 / calf - (4 mg of VM202 / calf)~Day 14 - 32 injections / calf:~• 16 injections of 0.5mL of VM202 / calf - (4 mg of VM202 / calf)"

BIOLOGICAL

High Dose: 32 mg Engensis (VM202)

"Subjects in the High Dose Group (16 mg VM202 / leg) will receive the following intramuscular injections in each calf:~Day 0~• 32 injections of 0.5mL of VM202 / calf (8 mg of VM202 / calf)~Day 14~• 32 injections of 0.5mL of VM202 / calf (8 mg of VM202 / calf)"

OTHER

Control- Placebo (normal saline)

subjects will receive thirty-two (32) 0.5 mL injections of normal saline on Day 0 and Day 14.

Trial Locations (17)

10029

Mount Sinai Medical Center, New York

12208

The Neurosciences Institute Albany Medical College, Albany

23510

East Virginia Medical School Strelitz Diabetes Center, Norfolk

32806

Compass Research, Orlando

33418

Palm Beach Neurological Center, Palm Beach Gardens

60611

Northwestern University, Chicago

73104

University of Oklahoma Harold Hamm Diabetes Center, Oklahoma City

77030

Houston Neurocare, Houston

The Methodist Hospital, Houston

84132

University of Utah, Salt Lake City

94598

Diablo Clinical Research, Walnut Creek

98057

Rainier Clinical Research, Seattle

02115

Beth Israel Deaconess, Boston

463-707

Seoul National University Bundang Hospital, Seongnam

120-752

Yonsei University College of Medicine Severance Hospital, Seoul

422-711

Sejong General Hospital, Bucheon-si

150-713

The Catholic University of Korea Youido St. Mary's Hospital, Seoul

All Listed Sponsors
lead

Helixmith Co., Ltd.

INDUSTRY

NCT01475786 - Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathy | Biotech Hunter | Biotech Hunter