Sulforaphane-rich Broccoli Sprout Extract for Autism

PHASE2CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

November 30, 2013

Study Completion Date

November 30, 2013

Conditions
Autism
Interventions
DRUG

Sulforaphane-rich Broccoli Sprout Extract

"30 subjects will be randomly selected to receive sulforaphane-rich Broccoli Sprout Extract. The medication will be supplied and dispensed as No.1 size gelcaps (each gelcap containing \~ 250 mg sulforaphane rich Broccoli Sprout Extract, equivalent to \~ 50 µmol of sulforaphane). The dosage of sulforaphane will depend on subject's body weight:~1. Subjects with body weight less than 101 lbs will receive \~ 50 micromol sulforaphane per day (1 gelcap to be taken once a day)~2. Subjects with body weight 101 lbs to 199 lbs will receive \~ 100 micromol sulforaphane per day (2 gelcaps to be taken once a day)~3. Subjects with bidy weight \> 199 lbs will receive \~ 150 micromol sulforaphane per day (3 gelcaps to be taken once a day)"

DRUG

Placebo

15 subjects will be randomly selected to receive inactive placebo (Gelcaps identical in appearance to that of active medication and containing microcrystalline cellulose)

Trial Locations (1)

02421

Lurie Center for Autism, MassGeneral Hospital for Children, Lexington

All Listed Sponsors
collaborator

Johns Hopkins University

OTHER

lead

Andrew Zimmerman

OTHER

NCT01474993 - Sulforaphane-rich Broccoli Sprout Extract for Autism | Biotech Hunter | Biotech Hunter