A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma

PHASE2CompletedINTERVENTIONAL
Enrollment

91

Participants

Timeline

Start Date

November 30, 2011

Primary Completion Date

December 31, 2013

Study Completion Date

December 31, 2013

Conditions
Glioblastoma Multiforme
Interventions
DRUG

bevacizumab [Avastin]

10 mg/kg every 2 weeks intravenously until disease progression or unacceptable toxicity

DRUG

fotemustine

75 mg/m2 intravenously on days 1, 8 and 15 followed by, after a 5 weeks interval, 100 mg/m2 on day 1 of a 3-weeks cycle. Until disease progression or unacceptable toxicity

Trial Locations (10)

16128

Genoa

20132

Milan

20133

Milan

31100

Treviso

35128

Padua

40133

Bologna

71013

San Giovanni Rotondo

80131

Napoli

00168

Rome

05100

Terni

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT01474239 - A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma | Biotech Hunter | Biotech Hunter