Nivolumab (BMS-936558; MDX-1106) in Combination With Sunitinib, Pazopanib, or Ipilimumab in Subjects With Metastatic Renal Cell Carcinoma (RCC) (CheckMate 016)

PHASE1CompletedINTERVENTIONAL
Enrollment

194

Participants

Timeline

Start Date

February 9, 2012

Primary Completion Date

February 2, 2016

Study Completion Date

June 3, 2021

Conditions
Renal Cell CarcinomaClear-cell Metastatic Renal Cell Carcinoma
Interventions
BIOLOGICAL

Nivolumab

BIOLOGICAL

Pazopanib

DRUG

Sunitinib

BIOLOGICAL

Ipilimumab

Trial Locations (14)

10065

Memorial Sloan Kettering Nassau, New York

19111

Fox Chase Cancer Center, Philadelphia

21287

Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins, Baltimore

28204

Blumenthal Cancer Center, Charlotte

37203

Tennessee Oncology, PLLC, Nashville

44195

Cleveland Clinic, Cleveland

91010-3000

City Of Hope, Duarte

02215

Beth Israel Deaconess Medical Center, Boston

03756

Dartmouth-Hitchcock Medical Center, Lebanon

77030-4009

University Of Texas M.D. Anderson Cancer Center, Houston

T2N 4N2

Tom Baker Cancer Centre, Calgary

T6G 1Z2

Cross Cancer Institute, Edmonton

V5Z 4E6

BC Cancer Agency - Vancouver Centre, Vancouver

M5G 1Z5

Princess Margaret Cancer Centre, Toronto

Sponsors
All Listed Sponsors
collaborator

Ono Pharmaceutical Co. Ltd

INDUSTRY

lead

Bristol-Myers Squibb

INDUSTRY

NCT01472081 - Nivolumab (BMS-936558; MDX-1106) in Combination With Sunitinib, Pazopanib, or Ipilimumab in Subjects With Metastatic Renal Cell Carcinoma (RCC) (CheckMate 016) | Biotech Hunter | Biotech Hunter