Assess Safety and Efficacy of ELAD (Extracorporeal Liver Assist System) in Subjects With Alcohol-Induced Liver Failure

PHASE3CompletedINTERVENTIONAL
Enrollment

203

Participants

Timeline

Start Date

February 28, 2013

Primary Completion Date

January 31, 2015

Study Completion Date

August 31, 2015

Conditions
Acute Alcoholic Hepatitis
Interventions
BIOLOGICAL

ELAD treatment

ELAD treatment consists of treatment with an extracorporeal liver assist system.

OTHER

Standard of care (Control)

Control receives standard medical treatment.

Trial Locations (45)

2050

Royal Prince Alfred Hospital, Camperdown

5042

Flinders Medical Centre, Bedford Park

6009

Sir Charles Gairdner Hospital, Perth

10016

New York University Langone Medical Center, New York

10032

Columbia University Medical Center, New York

10467

Montefiore Medical Center, The Bronx

10595

Westchester Medical Center, Valhalla

11030

North Shore University Hospital, Manhasset

15216

University of Pittsburgh Medical Center, Pittsburgh

19102

Drexel University College of Medicine, Philadelphia

19141

Albert Einstein Medical Center, Philadelphia

20007

Georgetown University Hospital, Washington D.C.

28034

Hospital Ramón y Cajal, Madrid

30309

Piedmont Atlanta Hospital, Atlanta

30322

Emory University Hospital, Atlanta

33136

University of Miami Hospital, Miami

33331

Cleveland Clinic Florida, Weston

33606

Tampa General Hospital, Tampa

39216

University of Mississippi Medical Center, Jackson

44195

Cleveland Clinic Foundation, Cleveland

55455

University of Minnesota - Twin Cities Campus, Minneapolis

60612

Rush University Medical Center, Chicago

72205

University of Arkansas for Medical Sciences, Little Rock

75203

Methodist Dallas Medical Center, Dallas

75246

Baylor University Medical Center, Dallas

78215

The University of Texas Health Science Center - Texas Liver Institute, San Antonio

84108

University of Utah Hospital, Salt Lake City

85008

Maricopa Integrated Health System (MIHS), Phoenix

85724

University of Arizona Medical Center, Tucson

90033

Keck Hospital of University of Southern California, Los Angeles

90048

Cedars-Sinai Medical Center, Los Angeles

92103

University of California San Diego Medical Center - Hillcrest, San Diego

92118

Sharp Coronado Hospital, Coronado

94304

Stanford School of Medicine/Stanford University Medical Center, Palo Alto

98104

Swedish Medical Center - Transplant Program, Seattle

University of Washington - Harborview Medical Center, Seattle

02114

Massachusetts General Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

08903

Rutgers University Hospital, New Brunswick

SE5 9RS

King's College Hospital, London

NW3 2QG

Royal Free Hospital, Hamstead

B152TH

University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham

BS2 8HW

United Hospitals Bristol NHS Foundation Trust, Bristol

CB20QQ

Cambridge University Hospitals NHS Foundation Trust, Cambridge

EH16 4SA

Royal Infirmary of Edinburgh, Edinburgh

All Listed Sponsors
lead

Vital Therapies, Inc.

INDUSTRY

NCT01471028 - Assess Safety and Efficacy of ELAD (Extracorporeal Liver Assist System) in Subjects With Alcohol-Induced Liver Failure | Biotech Hunter | Biotech Hunter