First In Human, Phase 1 Study of AG013736 In Patients With Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

November 30, 2002

Primary Completion Date

July 31, 2004

Study Completion Date

August 31, 2004

Conditions
Advanced Solid Tumors
Interventions
DRUG

AG-013736

Axitinib continuous oral dosing (10 mg once a day, 10 mg twice a day, 20 mg twice a day or 30 mg twice day) in the fed state

DRUG

AG-013736

Axitinib continuous oral dosing (20 mg twice a day) in the fed state

DRUG

AG-013736

Axitinib continuous oral dosing (5 mg twice a day) in the fed state

DRUG

AG-013736

Axitinib continuous oral dosing (15 mg once a day) in the fed state

DRUG

AG-013736

Axitinib continuous oral dosing (5 mg twice a day) in the fasted state

DRUG

AG-013736

Axitinib continuous oral dosing (2 mg twice a day on the first day of dosing, followed by 5 mg twice a day) in the fasted state

Trial Locations (3)

53792

Pfizer Investigational Site, Madison

77030

Pfizer Investigational Site, Houston

94115

Pfizer Investigational Site, San Francisco

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY