Methadone-Dolutegravir (DTG - GSK1349572) Drug Interaction Study.

PHASE1CompletedINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

February 29, 2012

Study Completion Date

February 29, 2012

Conditions
Infections, Human Immunodeficiency Virus and Hepatitis
Interventions
DRUG

Dolutegravir

Dolutegravir is an experimental drug in the integrase inhibitor class for the treatment of HIV. Dose of 50mg every 12 hours for 5 days.

DRUG

Methadone

Methadone is a synthetic opioid used in the treatment of opioid dependence. Subjects will be on individualize stabe dose for 8 days.

Trial Locations (1)

M5V 2T3

GSK Investigational Site, Toronto

Sponsors

Lead Sponsor

Collaborators (2)

All Listed Sponsors
collaborator

Shionogi

INDUSTRY

collaborator

GlaxoSmithKline

INDUSTRY

lead

ViiV Healthcare

INDUSTRY