A Safety and Efficacy Study of Carfilzomib and Pomalidomide With Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

November 30, 2011

Primary Completion Date

July 31, 2020

Study Completion Date

July 31, 2020

Conditions
Multiple Myeloma
Interventions
DRUG

Carfilzomib

IV over 30 minutes on Days 1,2,8,9,15, and 16 every 28 days

DRUG

Pomalidomide

PO daily on Days 1-21, every 28 Days

DRUG

Dexamethasone

40 mg weekly PO or IV on Days 1, 8, 15, and 22, every 28 days.

Trial Locations (9)

10032

Columbia University, New York

19105

University of Pennsylvania Abramson Cancer Center, Philadelphia

19111

Fox Chase Cancer Center, Philadelphia

27710

Duke University Medical Center, Durham

30322

Winship Cancer Institute of Emory University, Atlanta

46202

Indiana University Simon Cancer Center, Indianapolis

77030

MD Anderson Cancer Center, Houston

98109

Fred Hutchinson Cancer Research Center, Seattle

07601

The John Theurer Cancer Center @ Hackensack UMC, Hackensack

Sponsors

Lead Sponsor

Collaborators (2)

All Listed Sponsors
collaborator

Amgen

INDUSTRY

collaborator

Celgene Corporation

INDUSTRY

lead

Criterium, Inc.

INDUSTRY