Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 31, 2012

Primary Completion Date

December 31, 2013

Study Completion Date

March 31, 2014

Conditions
Childhood Cerebellar Anaplastic AstrocytomaChildhood Cerebral Anaplastic AstrocytomaChildhood Cerebral AstrocytomaChildhood Infratentorial EpendymomaChildhood Mixed GliomaChildhood OligodendrogliomaChildhood Supratentorial EpendymomaRecurrent Childhood Cerebellar AstrocytomaRecurrent Childhood Cerebral AstrocytomaRecurrent Childhood EpendymomaRecurrent Childhood Subependymal Giant Cell Astrocytoma
Interventions
OTHER

Diagnostic Laboratory Biomarker Analysis

Correlative studies

OTHER

Pharmacological Study

Correlative studies

DRUG

Sunitinib Malate

Given PO

Trial Locations (96)

2031

Sydney Children's Hospital, Randwick

2145

The Children's Hospital at Westmead, Westmead

4029

Royal Brisbane and Women's Hospital, Herston

Royal Children's Hospital-Brisbane, Herston

6008

Princess Margaret Hospital for Children, Perth

10016

Laura and Issac Perlmutter Cancer Center at NYU Langone, New York

10032

Columbia University Medical Center, New York

10065

Memorial Sloan-Kettering Cancer Center, New York

13210

State University of New York Upstate Medical University, Syracuse

14263

Roswell Park Cancer Institute, Buffalo

15224

Children's Hospital of Pittsburgh of UPMC, Pittsburgh

17033

Penn State Hershey Children's Hospital, Hershey

19104

Children's Hospital of Philadelphia, Philadelphia

Children's Oncology Group, Philadelphia

19803

Alfred I duPont Hospital for Children, Wilmington

20010

Children's National Medical Center, Washington D.C.

23298

Virginia Commonwealth University/Massey Cancer Center, Richmond

27157

Wake Forest University Health Sciences, Winston-Salem

27599

University of North Carolina at Chapel Hill, Chapel Hill

28203

Carolinas Medical Center/Levine Cancer Institute, Charlotte

29605

BI-LO Charities Children's Cancer Center, Greenville

Greenville Cancer Treatment Center, Greenville

30322

Children's Healthcare of Atlanta - Egleston, Atlanta

31404

Memorial University Medical Center, Savannah

32207

Nemours Children's Clinic-Jacksonville, Jacksonville

32504

Nemours Children's Clinic - Pensacola, Pensacola

32803

Florida Hospital Orlando, Orlando

32806

Nemours Children's Clinic - Orlando, Orlando

33607

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa

33701

All Children's Hospital, St. Petersburg

33901

Lee Memorial Health System, Fort Myers

33908

Golisano Children's Hospital of Southwest Florida, Fort Myers

35233

Children's Hospital of Alabama, Birmingham

University of Alabama at Birmingham Cancer Center, Birmingham

38105

St. Jude Children's Research Hospital, Memphis

39216

University of Mississippi Medical Center, Jackson

40202

Kosair Children's Hospital, Louisville

40536

University of Kentucky/Markey Cancer Center, Lexington

43205

Nationwide Children's Hospital, Columbus

43606

The Toledo Hospital/Toledo Children's Hospital, Toledo

44106

Rainbow Babies and Childrens Hospital, Cleveland

44308

Children's Hospital Medical Center of Akron, Akron

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

45404

Dayton Children's Hospital, Dayton

46202

Riley Hospital for Children, Indianapolis

46260

Saint Vincent Hospital and Health Services, Indianapolis

48201

Wayne State University/Karmanos Cancer Institute, Detroit

50309

Blank Children's Hospital, Des Moines

53226

Midwest Children's Cancer Center, Milwaukee

53792

University of Wisconsin Hospital and Clinics, Madison

54301

Saint Vincent Hospital, Green Bay

55404

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis

55455

University of Minnesota Medical Center-Fairview, Minneapolis

60611

Lurie Children's Hospital-Chicago, Chicago

60612

University of Illinois, Chicago

61637

Saint Jude Midwest Affiliate, Peoria

63110

Washington University School of Medicine, St Louis

63141

Mercy Hospital Saint Louis, St Louis

64108

The Childrens Mercy Hospital, Kansas City

72205

University of Arkansas for Medical Sciences, Little Rock

73104

University of Oklahoma Health Sciences Center, Oklahoma City

75230

Medical City Dallas Hospital, Dallas

75390

UT Southwestern/Simmons Cancer Center-Dallas, Dallas

76104

Cook Children's Medical Center, Fort Worth

77030

Baylor College of Medicine, Houston

78229

University of Texas Health Science Center at San Antonio, San Antonio

78411

Driscoll Children's Hospital, Corpus Christi

78723

Dell Children's Medical Center of Central Texas, Austin

84113

Primary Children's Hospital, Salt Lake City

87106

University of New Mexico Cancer Center, Albuquerque

90027

Children's Hospital Los Angeles, Los Angeles

90242

Southern California Permanente Medical Group, Downey

90806

Miller Children's and Women's Hospital Long Beach, Long Beach

92123

Rady Children's Hospital - San Diego, San Diego

92868

Children's Hospital of Orange County, Orange

94143

UCSF Medical Center-Parnassus, San Francisco

94304

Lucile Packard Children's Hospital Stanford University, Palo Alto

97239

Oregon Health and Science University, Portland

98105

Seattle Children's Hospital, Seattle

98405

Mary Bridge Children's Hospital and Health Center, Tacoma

99204

Providence Sacred Heart Medical Center and Children's Hospital, Spokane

93636-8762

Children's Hospital Central California, Madera

06106

Connecticut Children's Medical Center, Hartford

02115

Dana-Farber Cancer Institute, Boston

03756

Dartmouth Hitchcock Medical Center, Lebanon

07601

Hackensack University Medical Center, Hackensack

07960

Morristown Medical Center, Morristown

07902

Overlook Hospital, Summit

10467-2490

Montefiore Medical Center - Moses Campus, The Bronx

57117-5134

Sanford USD Medical Center - Sioux Falls, Sioux Falls

23708-2197

Naval Medical Center - Portsmouth, Portsmouth

B3K 6R8

IWK Health Centre, Halifax

L8N 3Z5

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton

H3H 1P3

The Montreal Children's Hospital of the MUHC, Montreal

H3T 1C5

Centre Hospitalier Universitaire Sainte-Justine, Montreal

G1V 4G2

Centre Hospitalier Universitaire de Quebec, Québec

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT01462695 - Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma | Biotech Hunter | Biotech Hunter