Concurrent Chemoradiotherapy With Famitinib for Patients With Locally Advanced Nasopharyngeal Carcinoma

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

August 31, 2015

Study Completion Date

January 31, 2016

Conditions
Locally Advanced Nasopharyngeal Carcinoma
Interventions
DRUG

Famitinib

Either at 12.5 mg, 16.5 mg、20 mg or 25 mg qd p.o., 2 weeks before concurrent chemoradiotherapy and D1-D49, exception D1, D22, and D43.

DRUG

Cisplatin

100 mg/m2, D1, D22, and D43(q3w)

RADIATION

radiation(IMRT)

IMRT (Intensity-Modulated Radiation Therapy). Radiation is delivered to GTV at 70 Gy in 32-33 fractions, CTV1 at 60 Gy in 32-33 fractions and CTV2 at 54 Gy in 32-33 fractions

Trial Locations (1)

Unknown

Department of Medical Oncology, Cancer Center, Sun Yet-sen University, Guangzhou

All Listed Sponsors
collaborator

Sun Yat-sen University

OTHER

lead

Jiangsu HengRui Medicine Co., Ltd.

INDUSTRY

NCT01462474 - Concurrent Chemoradiotherapy With Famitinib for Patients With Locally Advanced Nasopharyngeal Carcinoma | Biotech Hunter | Biotech Hunter