Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260)

PHASE3CompletedINTERVENTIONAL
Enrollment

660

Participants

Timeline

Start Date

January 13, 2012

Primary Completion Date

June 6, 2013

Study Completion Date

June 7, 2013

Conditions
Type 2 Diabetes Mellitus
Interventions
DRUG

Sitagliptin

Sitagliptin 100 mg tablet once daily for 24 weeks

DRUG

Comparator: Placebo

Placebo to sitagliptin once daily for 24 weeks

BIOLOGICAL

Insulin Glargine

Participants on insulin glargine or another insulin regimen for at least 10 weeks prior to screening will continue or switch to open-label insulin glargine once-daily in the evening for the duration of the study.

DRUG

Metformin

Participants on metformin oral tablet(s) at a dose of at least 1500 mg/day for at least 10 weeks prior to screening will continue receiving metformin at their current dose for the duration of the study.

All Listed Sponsors
lead

Merck Sharp & Dohme LLC

INDUSTRY

NCT01462266 - Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260) | Biotech Hunter | Biotech Hunter