Multi-center Study of Myeloablative Allo Stem Cell Transplant for Non-remission AML Using CloBu4 Regimen

PHASE2CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

November 30, 2011

Primary Completion Date

November 30, 2014

Study Completion Date

June 14, 2016

Conditions
Acute Myeloblastic Leukemia
Interventions
DRUG

Clofarabine/Busulfan x 4

"* Clofarabine IV dose level: 40 mg/m2/day x 5 days~* Busulfan IV dose level: 3.2 mg/kg daily x 4 days"

PROCEDURE

Peripheral blood stem cell transplant

Peripheral blood stem cell transplant, after pre-conditioning drug treatment

Trial Locations (12)

19104

University of Pennsylvania, Philadelphia

35233

University of Alabama, Birmingham, Birmingham

37232

Vanderbuilt University, Nashville

48109

University of Michigan Cancer Center, Ann Arbor

53226

Medical College of Wisconsin, Milwaukee

63110

Washington University at St Louis, St Louis

66160

University of Kansas Medical Center, Kansas City

91010

City of Hope National Medical Center, Duarte

98109

University of Washington, Seattle

07601

Hackensack University Medical Center, Hackensack

M5G 1X8

Hospital for Sick Children, Toronto

M5G 2M9

Princess Margaret Hospital, Toronto

All Listed Sponsors
collaborator

Genzyme, a Sanofi Company

INDUSTRY

collaborator

Otsuka Pharmaceutical Development & Commercialization, Inc.

INDUSTRY

lead

University of Michigan Rogel Cancer Center

OTHER

NCT01457885 - Multi-center Study of Myeloablative Allo Stem Cell Transplant for Non-remission AML Using CloBu4 Regimen | Biotech Hunter | Biotech Hunter