24
Participants
Start Date
November 30, 2011
Primary Completion Date
December 31, 2011
Study Completion Date
December 31, 2011
AZD3241 ER formulation 1
Oral tablets, 100mg bd on Day 1 to Day 2, 200mg bd on Day3, 300mg bd on Day 4 to Day7 and 300mg Once daily on Day 8 with High Fat Breakfast
Placebo
Placebo will be administered with the same intervention scheme as intervention 1 and 2
AZD3241 Alternative titration scheme with formulation 1 or 2
50 mg oral dose bd on Day 1, 100 mg oral dose bd on Day 2 and 3, 200 mg oral dose bd on Day 4, 300 mg oral dose bd on Day 5 to 7 and 300 mg once in the morning on Day 8
Research site, London
Lead Sponsor
AstraZeneca
INDUSTRY