Wake up Symptomatic Stroke - Benefit of Intravenous Clot Busters or Endovascular Intervention

PHASE2UnknownINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

November 30, 2011

Primary Completion Date

December 31, 2013

Study Completion Date

February 28, 2014

Conditions
Stroke
Interventions
DRUG

Anti-platelets and statin

DRUG

alteplase

"Full dose Intravenous thrombolysis~* 0.9 mg/kg~* Maximum dose is 90 mg~* 10% of the dose will be given over one minute~* 90% of the dose will be infused over 1 hour~* Admission to Neuro Intensive Care Unit(NICU) for 24 hours if no complications~* Neuro checks every 5 minutes during the infusion~* Neuro checks every hour after the infusion for 24 hours"

PROCEDURE

intra arterial intervention

"1. Intra arterial Activase (Maximum dose of 22 mg)~2. MERCI device (Maximum of 3 tries per device, no standard time frame for how long the procedure takes)~3. PENUMBRA device (no standard time frame for how long the procedure takes)"

Trial Locations (1)

14209

RECRUITING

Millard Fillmore Gates Circle Hospital, Buffalo

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

University at Buffalo Neurosurgery

OTHER

collaborator

Genentech, Inc.

INDUSTRY

lead

Jacobs Neurological Institute

OTHER