Post-occlusive Reactive Hyperemia and Basal-cell Carcinoma

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

June 30, 2011

Primary Completion Date

October 31, 2011

Study Completion Date

October 31, 2011

Conditions
Carcinoma, Basal Cell
Interventions
PROCEDURE

BCC surgery

This clinical trial will use skin flap model for trunk and facial BCC, with respect the classical excision margin of BCC surgery (3-4mm): after local anesthesia, a little random pattern skin flap will be raised around the BCC, then the cutaneous pedicle will be clamped with surgical clamp for 3 minutes and clamp released.

OTHER

Tourniquet ischemia

In case of limb BCC, limb tourniquet will be used, and occluded during 3 minutes upstream to the BCC location.

OTHER

Laser speckle imaging

During all steps of experimentation, laser speckle imaging will be used to measure continuously the peri-tumoral and tumoral perfusion, start from tumor excision, up to10 minutes after tumor pedicle clamp or tourniquet release.

Trial Locations (1)

75005

Institut Curie, Paris

All Listed Sponsors
lead

Institut Curie

OTHER

NCT01455363 - Post-occlusive Reactive Hyperemia and Basal-cell Carcinoma | Biotech Hunter | Biotech Hunter