Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

255

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

August 31, 2013

Study Completion Date

August 31, 2013

Conditions
Alzheimer DiseaseCognitive Impairment
Interventions
DRUG

Sodium oligo-mannurarate 600mg

sodium oligo-mannurarate capsule 600mg twice a day for 24 weeks

DRUG

Sodium oligo-mannurarate 900mg

sodium oligo-mannurarate capsule 900mg twice a day for 24 weeks

DRUG

Placebo

simulant of sodium oligo-mannurarate capsule

Trial Locations (24)

100005

Beijing Hospital, Beijing

110001

The First Affliated Hospital of Chinese Medical University, Shenyang

150001

The First Affliated Hospital of Harbin Medical University, Harbin

200011

The Ninth Hospital, Shanghai Jiao Tong University school of Medicine, Shanghai

200030

Shanghai Mental Health Center , Shanghai Jiao Tong University school of Medicine, Shanghai

210029

The Affliated Brain Hospital of Nanjing Medical University, Nanjing

214151

Wuxi Mental Health Center, Wuxi

250012

Qilu Hospital of Shandong University, Jinan

250021

Shandong Provincial Hospital, Jinan

250033

The Second Hospital of Shandong University, Jinan

300052

Tianjin Medical University General Hospital, Tianjin

310016

Sir Run Run Shaw Hospital, Medical college of Zhejiang University, Hangzhou

400010

Chongqing Medical University Second Affiliated Hospital, Chongqing

400038

The First Affliated Hospital of Third Military Medical University, Chongqing

400042

The Third Affliated Hospital of Third Military Medical University, Chongqing

410005

Hunan Provincial People's Hospital, Changsha

430070

Wuhan General Hospital of Guangzhou Military of People's Military Army, Wuhan

430077

Zhongnan Hospital of Wuhan University, Wuhan

510120

Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou

510170

Guangzhou Brain Hospital, Guangzho

610041

West China Hospital, West China School of Medicine Sichuan University, Chengdu

710038

Tangdu Hospital of The Forth Military Medical University of PLA, Xi’an

075000

The 251 Hospital of People's Liberation Army, Zhangjiakou

014040

The Central Hospital of Baotou, Baotou

All Listed Sponsors
collaborator

Shanghai Mental Health Center

OTHER

lead

Shanghai Greenvalley Pharmaceutical Co., Ltd.

INDUSTRY

NCT01453569 - Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease | Biotech Hunter | Biotech Hunter