Cellular Immunity in Adult Hepatitis B-vaccinated Serologic Non-responders

PHASE4UnknownINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

July 31, 2013

Study Completion Date

July 31, 2013

Conditions
Hepatitis B
Interventions
BIOLOGICAL

Twinrix

"A total of 400 healthy volunteers receive a standard course of immunization with a combined hepatitis A and B vaccine (Twinrix®) at 0, 1, and 6 months.~Twinrix ® Adult suspension for injection. 1 ml contains 720 ELISA units of hepatitis A virus antigen adsorbed to aluminum hydroxide and 20 micrograms hepatitis B surface antigen (HBsAg) adsorbed to aluminum phosphate in sterile water. Excipient: sodium chloride. Contains traces of neomycin."

Trial Locations (1)

8200

Department of Infectious Diseases, Aarhus University Hospital, Aarhus N

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Aarhus University Hospital

OTHER

collaborator

Monash Medical Centre

OTHER

lead

University of Aarhus

OTHER