A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers

PHASE1CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

November 30, 2013

Study Completion Date

June 30, 2014

Conditions
Colorectal CancerSquamous Cell Head and Neck CancerNon-small Cell Lung CancerTriple Negative Breast CancerOther Tumors With EGFR Dependence
Interventions
DRUG

MM-121

escalating doses MM-121 IV QW

DRUG

Irinotecan

180 mg/m2 IV Q2W

DRUG

Cetuximab

escalating doses cetuximab IV QW

Trial Locations (4)

27599

Chapel Hill

84112

Salt Lake City

94115

San Francisco

02115

Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Sanofi

INDUSTRY

lead

Merrimack Pharmaceuticals

INDUSTRY