136
Participants
Start Date
June 24, 2014
Primary Completion Date
April 13, 2017
Study Completion Date
April 21, 2017
aprepitant
On day 1, eligible patients will receive a single oral dose of Aprepitant 125 mg p.o, 1 hour before first dose of the 5-day oral temozolomide regimen. This will be followed by Aprepitant 80 mg p.o. on days 2 -5 (1 hour prior to temozolomide).
ondansetron
On Days 1-5, eligible patients will receive a single oral dose of Ondansetron, 30 minutes before first dose of the 5 -day oral temozolomide regimen.
The Preston Robert Tisch Brain Tumor Center at Duke, Durham
Merck Sharp & Dohme LLC
INDUSTRY
Katy Peters
OTHER