Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK)

PHASE2CompletedINTERVENTIONAL
Enrollment

264

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

January 31, 2014

Study Completion Date

January 31, 2014

Conditions
Fuchs' DystrophyBullous Keratopathy
Interventions
DRUG

Prednisolone acetate

Subjects assigned to Treatment Regimen A will instill 1 drop of prednisolone acetate 1% four times a day in the transplant eye for 3 months, then 3 times a day for one month, then twice a day for one month, then once a day until the subject exits the study.

DRUG

Fluorometholone

Subjects assigned to Treatment Regimen B will instill 1 drop of prednisolone acetate 1% four times a day in the transplant eye for one month. Then they will instill one drop of fluorometholone four times a day in the transplant eye for 2 months, then 3 times a day for 1 month, then twice a day for 1 month, then once a day until the subject exits the study.

Trial Locations (2)

46260

Price Vision Group, Indianapolis

Unknown

University of Erlangen, Erlangen

All Listed Sponsors
lead

Price Vision Group

INDUSTRY

NCT01448213 - Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK) | Biotech Hunter | Biotech Hunter