3,800
Participants
Start Date
June 13, 2012
Primary Completion Date
October 22, 2017
Study Completion Date
November 20, 2017
Hydrocortisone
Hydrocortisone 100mg vial (blinded) is reconstituted with 2ml of water for Injection, agitated for 20 seconds, rested for 3 minutes, contents of vial aspirated and added to 100ml bag of normal saline or 5% dextrose and given intravenously as a continuous infusion at rate of 200mg/per day for 7 days.
Sterile air filled vial
"the sterile air filled vial (blinded) is reconstituted with 2ml of water for Injection, agitated for 20 seconds, rested for 3 minutes, contents of vial aspirated and added to 100ml bag of normal saline or 5% dextrose and given intravenously as a continuous infusion. 2 sterile air filled vials per day for 7 days"
Auckland City Hospital (CVICU), Auckland
Auckland City Hospital (DCCM), Auckland
Middlemore Hospital, Auckland
Liverpool Hospital, Liverpool
The George Institute for Global Health, Sydney
St Vincent's Hospital, Darlinghurst
Prince of Wales Hospital, Randwick
Royal Prince Alfred Hospital, Camperdown
Royal North Shore Hospital, St Leonards
Rigshospitalet, Copenhagen
Blacktown Hospital, Blacktown
St George Hospital, Kogarah
Gosford Hospital, Gosford
Calvary Mater Hospital (Newcastle), Waratah
John Hunter Hospital, Newcastle
Tamworth Rural Referral Hospital, Tamworth
Tweed Heads District Hospital, Tweed Heads
Wollongong Hospital, Wollongong
Nepean Hospital, Penrith
Footscray Hospital, Footscray
Sunshine Hospital, St Albans
Royal Melbourne Hospital, Parkville
St Vincent's Hospital (Melbourne), Fitzroy
Northern Hospital, Epping
Austin Hospital, Heidelberg
Tauranga Hospital, Tauranga
Monash Medical Centre, Clayton
Geelong Hospital (Barwon Health), Geelong
Waikato Hospital, Hamilton
Bendigo Hospital, Bendigo
Redcliffe Hospital, Redcliffe
Royal Brisbane and Women's Hospital, Herston
Prince Charles Hospital, Brisbane
Wesley Hospital, Auchenflower
Mater Health Services, Brisbane
Princess Alexandra Hospital, Woolloongabba
Logan Hospital, Logan City
Gold Coast University Hospital, Gold Coast
Ipswich Hospital, Ipswich
Toowoomba Hospital, Toowoomba
Nambour Hospital, Nambour
Mackay Base Hospital, Mackay
Townsville Hospital, Townsville
Royal Adelaide Hospital, Adelaide
The Queen Elizabeth Hospital, Woodville South
Lyell McEwin Hospital, Elizabeth Vale
Royal Perth Hospital, Perth
Wellington Hospital, Wellington
Fiona Stanley Hospital, Murdoch
St John of God Hospital-Murdoch, Perth
Fremantle Hospital, Fremantle
Royal Hobart Hospital, Hobart
Christchurch Hospital, Christchurch
King Abdulaziz Medical City, Riyadh
King Khalid University Hospital, King Saud University, Riyadh
King Fahad Medical City, Riyadh
Royal Darwin Hospital, Darwin
North Shore Hospital, North Shore
Bristol Royal Infirmary, Bristol
Ashford & St.Peter's NHS Foundation Trust, Chertsey
Queen Alexandra Hospital (Portsmouth), Cosham
Queen Elizabeth Hospital Birmingham, Edgbaston
Royal Surrey County Hospital, Guildford
Lewisham Healthcare NHS Trust, London
Guy's and St Thomas' HNS Foundation Trust, London
King's College Hospital NHS Foundation Trust, London
St Georges Healthcare NHS Trust, London
Freeman Hospital, Newcastle upon Tyne
University Hospital Southampton, Southampton
Royal Gwent Hospital, Newport
National Health and Medical Research Council, Australia
OTHER
Australian and New Zealand Intensive Care Society Clinical Trials Group
NETWORK
The George Institute
OTHER