Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

43

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

November 30, 2013

Study Completion Date

January 31, 2014

Conditions
Solid Tumors
Interventions
DRUG

MM-121

MM-121 administered at 20 mg/kg IV loading dose followed by12mg/kg/week IV or 40 mg/kg IV loading dose followed by 20mg/kg/week IV

DRUG

Carboplatin

administered at AUC 6

DRUG

Pemetrexed

administered IV at 500 mg/m2

DRUG

Cabazitaxel

administered IV at 20 mg/m2 or 25 mg/m2

DRUG

Gemcitabine

administered IV at 1000 mg/m2 or 1250 mg/m2

Trial Locations (5)

14263

Buffalo

19111

Philadelphia

45267

Cincinnati

47905

Lafayette

Unknown

Villejuif

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Sanofi

INDUSTRY

lead

Merrimack Pharmaceuticals

INDUSTRY

NCT01447225 - Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter