NCT01446016View on ClinicalTrials.gov

Chloroquine With Taxane Chemotherapy for Advanced or Metastatic Breast Cancer After Anthracycline Failure (CAT)

PHASE2CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

September 30, 2011

Primary Completion Date

March 1, 2019

Study Completion Date

March 1, 2019

Conditions
Breast NeoplasmsBreast Cancer
Interventions
DRUG

Paclitaxel

Chloroquine 250mg po daily together with Paclitaxel (Taxane) 175 mg/m2 three hours infusion every three weeks.

DRUG

Docetaxel

Chloroquine 250mg po daily together with docetaxel 75 mg/m2 administered intravenously over one hour every three weeks

DRUG

Abraxane

Chloroquine 250mg po daily together with Abraxane 260 mg/m2 administered intravenously over 30 minutes every three weeks.

DRUG

Ixabepilone

Chloroquine 250mg po daily together with Ixabepilone is 40 mg/m2 administered intravenously over three hours every three weeks.

Trial Locations (3)

77030

Houston Methodist Hospital Cancer Center, Houston

77070

Houston Methodist Hospital Willowbrook, Houston

77479

Houston Methodist Hospital Sugar Land, Sugar Land

All Listed Sponsors
lead

The Methodist Hospital Research Institute

OTHER

NCT01446016 - Chloroquine With Taxane Chemotherapy for Advanced or Metastatic Breast Cancer After Anthracycline Failure (CAT) | Biotech Hunter | Biotech Hunter