146
Participants
Start Date
August 31, 2011
Primary Completion Date
December 31, 2012
Study Completion Date
July 31, 2013
Meclizine
Pre-Quit Period: In this group, participants will take meclizine daily during the three week pre-quit period. The meclizine will be taken in two doses daily, one capsule with breakfast and one with dinner.
Nicotine Patch
"Pre-Quit Period: During weeks two and three, participants will apply active 21mg/24h nicotine patches daily.~Post-Quit Period: Following the quit-day these participants will apply active nicotine patches daily using the following dose schedule: 21mg/24h for four weeks, 14mg/24h for one week, and 7mg/24h for one week."
Placebo
Pre-Quit Period: In this group, participants will take placebo capsules daily during the three week pre-quit period. The placebo will be taken in two doses daily, one capsule with breakfast and one with dinner.
Duke Center for Nicotine and Smoking Cessation Research, Winston-Salem
Duke Center for Nicotine and Smoking Cessation Research, Raleigh
Duke Center for Nicotine and Smoking Cessation Research, Durham
Duke Center for Nicotine and Smoking Cessation Research, Charlotte
Lead Sponsor
Philip Morris USA, Inc.
INDUSTRY
Duke University
OTHER